(seq. 287)

278

Materia Medica

Stimulants

and from this circumstance he draws his conclusion the
experiments of Dr Crump are amongst the latest and
best and most conclusive in favor of the stimulating
properties of opium, he assures us they were made with the
utmost care and greatest attention to every particular that could
influence the result of them, having breakfasted says he
I took one grain of opium in a teaspoon full of water, my pulse
beat naturally at Seventy in a minute, in two minutes after
I took the opium it was at Seventy, and in

[minutes/beats] 5/74, 10/76, 15/75, 20/74, 30/72, 35/72, 40/72.

I could scarcely perceive any variation in the
strength and fulness of the pulse, and no drowsiness. I gave
(continued he) A young man whose pulse beat naturally 44 in
a minute one grain which produced the following variations

[minutes/beats] 5/44, 10/44, 15/44, 20/50, 30/52, 35/54, 40/45.

After twenty five minutes had elapsed
there was a manifest increase in the fulness and strength of the pulse
the man had never taken opium before, in the afternoon my pulse
beat at seventy I took grs ij [2 grains] of opium the result was as follows,

[minutes/beats] 5/44, 10/44, 15/44, 20/50, 30/52, 35/54, 40/45.

in 20 minutes the pulse
increased in fulness, in 40 minutes I experienced a language
pleasing sensation, and afterwards nausea, headache, drowsiness, and