(seq. 311)

302

Materia Medica

Stimulants

miasmata, Typhus by animal and the other by Vegitable
Miasmata. Genuine Typhus has been known to be produced by
a stagnant lake. Synochus and Typhus are in the beginning
I will not say inflamitory diseases, but the febrile symptoms
run verry high, for this reason I think opium must be
improper, and Dr Cullen is of the same opinion, he says
in many of the fevers of Scotland there appeared more or less
of the inflamitory diathesis in the system, and during this state
he holds and has often seen the use of opium to be injurious in
the extreme, it neither induces sleep or relieves pain but
agrevates the inflamitory symptoms and frequently determines
to particular inflamation and proves fatal.

Yellow Fever. I believe the matter producing this to be the same
with that of the Plague, after the inflamitory symptoms have
subsided, opium may be proper, but wine is here more generally
usefull, delirium often occurs with inflamitory symptoms and
the wine does harm, but there is a delirium in Typhus which
proceeds from debility where wine and opium will doubtless be
proper. Sydenham says opium should not be given before
the twelvth day of the disease, but I certaily should not wait