Sanitary medicine, exercise folio : a note Oct. 25, 1892 to Mar. 10, 1893

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it runs a regular course.

But if the patient is weak and the irregular form occurs it is very often fatal

Treatment Give good ventilation, good food and a constant temperature. Encourage the formation of abscesses by poulticing on a blister and then open them. If near the great vessels it is better to tear the tissues with the finger -- The following treatment is recommended -

Carlsbad Salt Sod Sulph. grams 75 Sod Chlor grams 20 Sod BiCarb grams 5

Electuary Sol Sulph grams 250

Antimony Blk Sod Sulph grams 25 Licorice root & treacle to form an electuary.

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-- " -- " -- Dec. 9, 1892, -- " -- " -- "

Tetanus or Lock Jaw This is an infective disease caused by a bacillus, which finds its way to the tissues by means of a wound, it multiplies locally, producing poisonous chemical substances, which are diffused throughout the system causing disease characterized by various contractions of the muscles.

[drawing of rod connected to spore] Rod spore [unlabeled drawing]

The bacillus producing tetanus is an obligatory anaerobic germ. It is found in rich garden soil, manure dust & etc. It is widely diffused to all parts of the world, resists the effects of putrefaction for a long period and grows best at a temperature of 36 to 38° C. It is said be slightly motile in liquids and produces disease by entering a surface

[24.?]

-generally, multiplies and produces alkaloidal poisons, which enter the blood stream. The germs do not enter the stream if so they are destroyed by the O in the blood. All animals are attacked by it but its is most common in the horse, ass & mule, and is most commonly seen in warm climates

3 poisonous alkaloids have been isolated by Briegen as follows:(1) Tetanin (2) Tetanotoxin (3) Spasmotoxin

Two forms of tetanus are described 1st Infectious, due to the above germ[illegible] 2nd Toxic, due to [illegible], thebaine &c Symptoms of the first or infectious form and classification (1) Trismus when the spasms are confined to the muscles of mastication

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(2) Orthotonus when the body is rigid and straight (3) Opisthotonus when it is curved, the curvature being down. (4) Pleurosthotonus when the head is curved to one side:

Symptoms Protrusion of the membrana nictitans from retraction of the eye ball Tail raised horizontally, great hyperthesia when touched or excited, & the production of spasms by so doing.

The pulse or temperature are not materially changed. Cyanosis is noticed, from the lungs not acting properly which produces the non oxygenation seen by examination of the visible mucous membrane. The faeces and urine are retained by non action of the organs in which they occur

The larger proportion of dogs recover from tetanus

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Treatment.Remove the animal from excitement, place in [illegible], give liquid food and remove the faeces and urine. Chlor. Hydrate, morphia and Gelsemium are recommended. And Tri Chlor. Iodine is a good germicide in this disease

Immunity is produced by the virus weakened by Tri Chlor Iodi, which is injected hypodermically. Blood serum taken from animals inoculated with the above and injected into those affected with the disease in the first stage, is said to have checked it

Antitoxin is the substance which neutralizes the effects produced by the germ.