Sanitary medicine, exercise folio : a note Oct. 25, 1892 to Mar. 10, 1893

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Pathological Anatomy 1st Hemorrhage in any part of the body (2nd) A gelatinous bloody infiltration, which may be yellow, transparent or streaked with blood, the mass resembling domestic -gelatine when prepared for -dessert. The character of the infiltration is a pathognomonic lesion of this disease. (3rd) The spleen is almost always unnaturally enlarged being sometimes twice the natural size. (4) The blood generally black, not coaguable and resembling tar (5) Presence of Bacillus Anthracis which is easiest formed in the capillaries of the spleen and liver

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The black tarry blood is generally found in and beneath the skin, the hemorrhages in loose connective tissue &, in the muscles, which are dark read and friable, and onerous membranes. The gelatine ocurring in masses in the loose connective tissue generally in the section around the trachea. Intestines bady congested. Endocardium stained a dark red color from a breaking down of the blood.

The spleen may be uniformily engorged or have large tumors The intestinal contents bloody The lungs ecchimosed & odematous Trachea & bronchii contain bloody mucosa Brain congested. Bones marked by bloody layers always haematuria

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The blood does not regain its red color when brought to the light Poikilocytosis an irregularity in the shape of the red blood corpuscle Leucocytosis a transient increase in the number of white corpuscles The carcass looses heat slowly after death, body swells enormously, rigor mortis incomplete, decomposition rapid and a discharge from the mouth, nose and anus of bloody mucous.

In the apoplectic form a great many of these lesions are absent.

Symptoms --

Invasion sudden and rapid in all forms, fever high, petechiae of visible mucous membranes, swelling [illegible] the body. The symptoms vary somewhat according to the organ effected Death generally occurs in from 1 to 3 days

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3 forms of Anthrax -1st - Acute 2nd - Sub acute 3rd - Apoplectic or Splenic Apoplexy Symptoms of the Apoplectic form --

The animal may be taken suddenly ill when eating or moving about and die immediately or in from 3 to 5 minutes. This form is most common in sheep. When cattle die from this form it is generally the fat ones and is the beginning of an outbreak.

Symptoms of the Acute form

Develops in from 10 to 24 hrs, temperature from 104 to 108°F., bellowing, and convulsions and bloody discharges. May have pulmonary [illegible] of brain symptoms, cyanosis visible mucous membranes of the head

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convulsions unsteadiness of gait and death from asphyxia

The animal may show signs of improvement and the symptoms return with greater severity and death ensue. This form is known as Intermittent Anthrax. (3) Sub Acute. (symptoms of)

The symptoms develop less rapidly and terminate in from 1 to 7 days

Horses show colicky pains and recoveries are much more common in this form. Malignant pustule is caused by the invasion of the bacilli themselves.

Both forms may be produced by feeding spores or innoculating rods under the skin