Jeffries, John, 1745-1819. Small Pocks, 1775-1779 (inclusive). B MS b1.2, Countway Library of Medicine.

{October} 13, Cato Brown, Nights not so restless, - Pul: Rubr: Sexta {quaque} Hora Dilution &c

{October} 14, Cato Brown, Pock filling upon Legs & Thighs, Ptyalism considerable, passed no Stool, - directed Enema, & to be repeated pro Re Nata . -

{October} 15, Cato Brown. Ptyalism continues - Bol. {Mercury} & Rhai - once in twelve hours - Laud: Lig: {quart} ++ , hora Lamni

Negro Woman, same house, Had small Pox slightly now desquaming - Sal: Cath. mane sumend . -

{October} 16, Cato Brown, Respiration difficult rather laboring, restless no sleep in Nights, Ptyalism decreased Hands &c not swelled, - Episp: ad bruch: - sinap: ad Plantar: Ped: - Pul Cath. - No discharge by Bowells Enema - Dilut. - slight Delirum - Infus: Cathart: Mane sumand, si Alvus non salvetur antea

{October} 17, Cato Brown, rested but little, difficulty of swallow ing, Pustules thin & watery & not concocted, almost constant tremor - Frequent dililirum & wandering - directed Hands . . .

to be put into warm water, - & warm {Pediluvium} - Has taken Infus: Cath: = passed one large good Stool, swelling of Face subsided - directed in Eve, warm {Pediluvium} &c to be repeated, - Sinap: to feet - Episp: ad sura, - Nourishment &c

{October} 18, Cato Brown, passed three Stools this day, swallows rather easier - In the Eve, slept several hours - delirious & discharges under him - some scabs fallen off from face; in hands &c, still [?] - dilution & nourishment

{October} 19, Cato Brown, passed 2 Stools in Night & 2 today drowsy, & delirious thru the Day, Difficult deglutition pulse loose & soft. - directed Nourishment & Wine, Linnen to be shifted - [Sinapisms?] &c

{October} 20, Cato Brown, died last Night at Midnight

{December} 31, Hurd, aged 12 years, had Symptoms of Small Pox fever, was ordered to keep abroad continually, use cold drinks & Daily purged with Sal. Cath. & Tart: Emet had eruption {January} 2d, distinct & good, Symptoms gone off

{January} 31, Peter, a Negro, third Day of Eruption, pustules very thick & rather flat. Pain & tension in abdomen, Salts & man: & ol: carysphil. - Dilution & cool {Regimen}

{February} 2, Peter Pocksmaturating, Face & Hands swollen -

Mrs ––– has great many pustules, but now desquaming cool regimen & lax bowells with Salts. &c

Mr Worrall, aged 7 years, great degree of Fever & lasi tude with Pain in Head & Back &c - continue - Salts & mann:& Tart: Emet. - operated very well - directed to go out in Air, to be supported as he was very giddy - Eruption appearing - Directed to keep out of Doors as much as possible - cool Drinks &c -

{February} 6, Mr Worrall comfortable, keep Bowells open

Peter, Face much swoln Respiration difficult, Nostril stuffed up, Decoct: apersen. ex Sence, Manna, Crem: Tart: & Sem: Coriand: tertia {quaque} hora . -

Mrs Howard, aged 67, & old Dysentric complaints, Now third Day of Eruption, pretty full all over Body, Face & Extremitys - Decoct: Cath.- Dilut: subacid & Emet - panca Vinora -

& same regimen continued - {January} 4, Ditto

Miss Sloper aged 5 years, taken ill at the same time Parents could not be persuaded to get her into the air &c has Eruption very thick & Symptoms have been much more severe than in hurd, & her Eyes were affec ted - Pulv: {Calomel} Tar: & Tart: Emet: & cold drinks & directed to keep up as much as possible - {January} 4

1776 {January} 7 Hurd, very comfortable Pocks fully ma turated & beginning to turn on face, has continued the Cool Regimen & exposure to Air &c from the first com plaining - Bowells occasionally moved by Sal. Cath. &c

Miss Sloper, Eruption completed, has Pustules thick all over, but distinct inflamed Bases & fill well - Rather continue Salts & man = salts & man. -

{January} 11, Hurd & Miss Sloper, Pustules desquaming .Cath. morrow have passed thru the Disorder very well - Cold Regimen

{February} 8, Peter died

{February} 11, Mrs Howard face swelled, as are Feet & Hands & Pocks much inflamed around Bases - sore Throat - Mist. Cath. - gave much care to throat - [Episp: & Sinah directed in care of subsiding of the Swelling on Pocks -

three Women, between the Age of 25 & 55, had small Pox, each of them very full of pustules, extremely Poor & exposed very much to severe weather by want of fuel & Cloaths - the youngest, a Girl of the Town, & I believe in 4th month of Pregnancy & infested with Lice besides - all Bowell kept lax & cool Regimen

{February} 14, Mrs Howard died, each Pock found became indent ed in Middle & changed to purple & livid colour -

2 Children attacked with small Pox, between Age of 3 & 6 years - cool Regimen & Cath: Mist. pro re nata